Dichloromethane → Trifluoroacetic acid

HRID 107829Notes

Reaction equation

HRID 107829 reaction equation
[C:1]([O:2][C:3](=[O:4])[NH:7][CH2:8][CH2:9][c:10]1[cH:11][c:12]([O:30][CH2:31][c:32]2[cH:33][cH:34][cH:35][cH:36][cH:37]2)[c:13]([N:16]2[S:17](=[O:28])(=[O:29])[N:18]([CH2:22][CH2:23][Si:24]([CH3:25])([CH3:26])[CH3:27])[C:19](=[O:21])[CH2:20]2)[cH:14][cH:15]1)([CH3:5])([CH3:6])[CH3:38].[Cl:46][CH2:47][Cl:48].[F:39][C:40]([C:41](=[O:42])[OH:43])([F:44])[F:45]>>[F:39][C:40]([C:41](=[O:42])[OH:43])([F:44])[F:45].[NH2:7][CH2:8][CH2:9][c:10]1[cH:11][c:12]([O:30][CH2:31][c:32]2[cH:33][cH:34][cH:35][cH:36][cH:37]2)[c:13]([N:16]2[S:17](=[O:28])(=[O:29])[N:18]([CH2:22][CH2:23][Si:24]([CH3:25])([CH3:26])[CH3:27])[C:19](=[O:21])[CH2:20]2)[cH:14][cH:15]1

Participants

5

Reactant 3

HCID 6344DichloromethaneHCID 6422Trifluoroacetic acidHCID 68842331(2-{3-Benzyloxy-4-[1,1,4-trioxo-5-(2-trimethylsilanylethyl)-1,2,5-thiadiazolidin-2-yl]-phenyl}-ethyl)-carbamic Acid Tert-butyl Ester

Product 2

HCID 6422Trifluoroacetic acidHCID 667572325-[4-(2-Aminoethyl)-2-phenylmethoxyphenyl]-1,1-dioxo-2-(2-trimethylsilylethyl)-1,2,5-thiadiazolidin-3-one

Sources & evidence

ORD record
ord-c0539fb7eacc4ed488ad2996d6297b65
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (2/10)

Reaction notes

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