Piperazine → HCID 19428498, compound

HRID 1078293Notes

Reaction equation

HRID 1078293 reaction equation
Cl[C:2]1[CH:7]=[C:6]([NH:8][CH2:9][C:10]([CH3:13])([CH3:12])[CH3:11])[N:5]=[C:4]([NH:14][CH2:15][C:16]([CH3:19])([CH3:18])[CH3:17])[N:3]=1.[NH:20]1[CH2:25][CH2:24][NH:23][CH2:22][CH2:21]1>>[CH3:17][C:16]([CH3:19])([CH3:18])[CH2:15][NH:14][C:4]1[N:5]=[C:6]([NH:8][CH2:9][C:10]([CH3:13])([CH3:12])[CH3:11])[CH:7]=[C:2]([N:20]2[CH2:25][CH2:24][NH:23][CH2:22][CH2:21]2)[N:3]=1

Participants

3

Reactant 2

HCID 4837PiperazineHCID 19428493HCID 19428493, compound

Product 1

HCID 19428498HCID 19428498, compoundYield 51.1%

Procedure

The reaction of 4-chloro-2,6-bis(2,2-dimethylpropylamino)pyrimidine with piperazine as described in Example 5 gives the title compound in a yield of 51.1%, m.p.:138°-140° C.

Sources & evidence

ORD record
ord-6f577877141e4dd7a1fc588d17ad19d8
Source dataset
uspto-grants-1996_08
Patent number
US05547949

Reaction notes

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