Piperazine → HCID 19429145, compound

HRID 1078295Notes

Reaction equation

HRID 1078295 reaction equation
[CH3:1][C:2]([CH3:18])([CH3:17])[CH2:3][NH:4][C:5]1[N:10]=[C:9](Cl)[CH:8]=[C:7]([N:12]2[CH2:16][CH2:15][CH2:14][CH2:13]2)[N:6]=1.[NH:19]1[CH2:24][CH2:23][NH:22][CH2:21][CH2:20]1>>[CH3:1][C:2]([CH3:18])([CH3:17])[CH2:3][NH:4][C:5]1[N:10]=[C:9]([N:19]2[CH2:24][CH2:23][NH:22][CH2:21][CH2:20]2)[CH:8]=[C:7]([N:12]2[CH2:16][CH2:15][CH2:14][CH2:13]2)[N:6]=1

Participants

3

Reactant 2

HCID 4837PiperazineHCID 19428538HCID 19428538, compound

Product 1

HCID 19429145HCID 19429145, compoundYield 76%

Procedure

(2,2-Dimethylpropylamino)-4-chloro-6-pyrrolidinopyrimidine is reacted with piperazine as described in Example 5 to obtain the title compound in a yield of 76%, m.p.:118°-120° C.

Sources & evidence

ORD record
ord-a2317be09eba43d8b0d2dd93b1dab6a8
Source dataset
uspto-grants-1996_08
Patent number
US05547949

Reaction notes

Loading…