Piperazine → HCID 19428551, compound

HRID 1078298Notes

Reaction equation

HRID 1078298 reaction equation
[CH2:1]1[CH2:27][O:26][C:3]2([CH2:8][CH2:7][N:6]([C:9]3[N:14]=[C:13](Cl)[CH:12]=[C:11]([N:16]4[CH2:21][CH2:20][C:19]5([O:25][CH2:24][CH2:23][O:22]5)[CH2:18][CH2:17]4)[N:10]=3)[CH2:5][CH2:4]2)[O:2]1.[NH:28]1[CH2:33][CH2:32][NH:31][CH2:30][CH2:29]1>>[CH2:1]1[CH2:27][O:26][C:3]2([CH2:8][CH2:7][N:6]([C:9]3[N:10]=[C:11]([N:16]4[CH2:21][CH2:20][C:19]5([O:25][CH2:24][CH2:23][O:22]5)[CH2:18][CH2:17]4)[CH:12]=[C:13]([N:28]4[CH2:33][CH2:32][NH:31][CH2:30][CH2:29]4)[N:14]=3)[CH2:5][CH2:4]2)[O:2]1

Participants

3

Reactant 2

HCID 4837PiperazineHCID 19428519HCID 19428519, compound

Product 1

HCID 19428551HCID 19428551, compoundYield 55.7%

Procedure

2,6-bis(4,4-Ethylenedioxy-1-piperidinyl)-4-chloropyrimidine is reacted with piperazine in the way described in Example 5 to obtain the title compound in a yield of 55.7%, m.p.:130°-140° C.

Sources & evidence

ORD record
ord-fbd1b36221e547b09861e468f39bd62e
Source dataset
uspto-grants-1996_08
Patent number
US05547949

Reaction notes

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