Cyclopentylamine → HCID 19428501, compound

HRID 1078307Notes

Reaction equation

Cl[C:2]1[N:7]=[C:6]([Cl:8])[CH:5]=[C:4]([Cl:9])[N:3]=1.[CH:10]1([NH2:15])[CH2:14][CH2:13][CH2:12][CH2:11]1>>[CH:10]1([NH:15][C:2]2[N:7]=[C:6]([Cl:8])[CH:5]=[C:4]([Cl:9])[N:3]=2)[CH2:14][CH2:13][CH2:12][CH2:11]1

Participants

Reactant 2

HCID 2906Cyclopentylamine

HCID 773782,4,6-Trichloropyrimidine

Product 1

HCID 19428501HCID 19428501, compoundYield 35.2%

Procedure

2,4,6-Trichloropyrimidine is reacted with cyclopentylamine according to the method of Example 3. The less polar 2-(cyclopentylamino)-4,6-dichloropyrimidine is obtained in a yield of 35.2%, m.p.:48°-52° C.

Sources & evidence

ORD record: ord-19b923077eda4a589b23c2e4b8b89a56
Source dataset: uspto-grants-1996_08
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US05547949

Reaction notes

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