Piperazine → HCID 19428507, compound

HRID 1078309Notes

Reaction equation

HRID 1078309 reaction equation
[CH:1]1([NH:6][C:7]2[N:12]=[C:11]([NH:13][CH:14]3[CH2:18][CH2:17][CH2:16][CH2:15]3)[CH:10]=[C:9](Cl)[N:8]=2)[CH2:5][CH2:4][CH2:3][CH2:2]1.[NH:20]1[CH2:25][CH2:24][NH:23][CH2:22][CH2:21]1>>[CH:1]1([NH:6][C:7]2[N:12]=[C:11]([NH:13][CH:14]3[CH2:18][CH2:17][CH2:16][CH2:15]3)[CH:10]=[C:9]([N:20]3[CH2:25][CH2:24][NH:23][CH2:22][CH2:21]3)[N:8]=2)[CH2:5][CH2:4][CH2:3][CH2:2]1

Participants

3

Reactant 2

HCID 4837PiperazineHCID 19428506HCID 19428506, compound

Product 1

HCID 19428507HCID 19428507, compoundYield 81.9%

Procedure

2,4-Bis(cyclopentylamino)-6-chloropyrimidine is reacted with piperazine according to the method of Example 4. The title compound is obtained in a yield of 81.9%, m.p.:142°-148° C.

Sources & evidence

ORD record
ord-cd18cdfe911846159b75c288cd0b77d6
Source dataset
uspto-grants-1996_08
Patent number
US05547949

Reaction notes

Loading…