HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-Chlorobenzaldehyde → HCID 19429422, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-Chlorobenzaldehyde | HCID 7726 | — |
| Reactant | Sodium borohydride | HCID 4311764 | — |
| Reactant | 4-Methyl-2-phenyl-1H-imidazole-1-propanamine | HCID 19429386 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | HCID 19429422 | HCID 19429422 | — |
Reaction Steps
3-(4-Methyl-2-phenylimidazol-1-yl)propylamine (5.5 g) and 4-chlorobenzaldehyde (3.6 g) were stirred in absolute ethanol (70 ml) for 16 hours. Sodium borohydride (2.0 g) was added and the mixture heated under reflux for 7 hours. Work-up as described in Example 42 gave N-(4-chlorobenzyl)-3-(4-methyl-2-phenylimidazol-1-yl)propylamine. Glc indicated that the product contained 13% (approx) of N-(4-chlorobenzyl)-3(5-methl-2-phenylimidazol-1-yl)propylamine.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05547972 |
| Source dataset | uspto-grants-1996_08 |
| ORD ID | ord-4ae285ae2f93489b98cdb962c39b5917 |
| Source note | uspto-grants-1996_08 |