HuagongsheHuagongshe Chemistry Print Report · For research reference only
Triethylamine → 4-chloro-N-[1-(4-chlorophenyl)-1-methylethyl]butyramide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Triethylamine | HCID 8471 | — |
| Reactant | 4-Chlorobutyryl chloride | HCID 78370 | — |
| Reactant | 2-(4-Chlorophenyl)propan-2-amine hydrochloride | HCID 45158337 | — |
| Solvent | Dichloromethane | HCID 6344 | — |
| Product | 4-chloro-N-[1-(4-chlorophenyl)-1-methylethyl]butyramide | HCID 19429521 | — |
Reaction Steps
In a similar manner to Example 52b, 1-(4-chlorophenyl)-1-methylethylamine hydrochloride (2.5 g) was treated with 4-chlorobutyryl chloride (1.7 g) in dichloromethane (30 ml) containing triethylamine (3.4 ml) to give 4-chloro-N-[1-(4-chlorophenyl)-1-methylethyl]butyramide which was used directly in part (b) below.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05547972 |
| Source dataset | uspto-grants-1996_08 |
| ORD ID | ord-54aec7b10ade49d5bda1b26a203ed4e8 |
| Source note | uspto-grants-1996_08 |