Potassium Hydroxide → HCID 10788561, compound

Participants

Reaction Conditions

Reaction Steps

2 g of potassium hydroxide are added to a solution of 1.20 g (2.72 mmol) of the diester obtained in Example 15 in 50 ml of n-butanol and the mixture is heated at 110° C. for 24 hours. After the same treatment as in Example 8, and recrystallization from the ethyl acetate-THF mixture, 605 mg (52%) of the expected derivative are isolated, which derivative melts at 333°-335° C.

Provenance & Evidence