HCID 10626406, compound → HCID 10389354, compound

Participants

Reaction Steps

4 g (7.32 mmol) of the ester obtained in Example 46, in solution in 100 ml of dioxane, are hydrogenated in the presence of 1.20 g of palladium on carbon (10%) under a hydrogen pressure of 7 bar, for 5 h at 50° C. After the same treatment as in Example 5, followed by a recrystallization from the ethanol/water mixture, 3 g (90%) of the expected derivative are isolated, which derivative melts at 258° C.

Provenance & Evidence