N-(2-Methoxyphenyl)piperazine hydrochloride → HCID 19428165, compound

HRID 1078578Notes

Reaction equation

HRID 1078578 reaction equation
CS(O[CH2:6][CH2:7][C:8]1[C:9](=[O:23])[O:10][C:11]2[CH:18]=[C:17]([O:19][CH3:20])[C:16]([O:21][CH3:22])=[CH:15][C:12]=2[C:13]=1[CH3:14])(=O)=O.Cl.[CH3:25][O:26][C:27]1[CH:32]=[CH:31][CH:30]=[CH:29][C:28]=1[N:33]1[CH2:38][CH2:37][NH:36][CH2:35][CH2:34]1>C(O)(C)C>[CH3:22][O:21][C:16]1[C:17]([O:19][CH3:20])=[CH:18][C:11]2[O:10][C:9](=[O:23])[C:8]([CH2:7][CH2:6][N:36]3[CH2:35][CH2:34][N:33]([C:28]4[CH:29]=[CH:30][CH:31]=[CH:32][C:27]=4[O:26][CH3:25])[CH2:38][CH2:37]3)=[C:13]([CH3:14])[C:12]=2[CH:15]=1

Participants

4

Reactant 2

HCID 9899402N-(2-Methoxyphenyl)piperazine hydrochlorideHCID 194281263-[2-(methanesulphonyloxy)ethyl]-6,7-dimethoxy-4-methyl-2H-1-benzopyran-2-one

Product 1

HCID 19428165HCID 19428165, compoundYield 14%

Reagents, catalysts & solvents 1

HCID 3776IsopropanolSolvent

Procedure

Process A; starting materials: 3-[2-(methanesulphonyloxy)ethyl]-6,7-dimethoxy-4-methyl-2H-1-benzopyran-2-one (Example 28) and 1-(2-methoxyphenyl)piperazine hydrochloride; yield 14%; m.p. 174°-175° C. (from isopropanol).

Sources & evidence

ORD record
ord-1accbd691c534a7da32e7ac41445fec6
Source dataset
uspto-grants-1996_08
Patent number
US05550129

Reaction notes

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