1-(2-Methoxyphenyl)piperazine → HCID 19428156, compound

HRID 1078581Notes

Reaction equation

HRID 1078581 reaction equation
[CH2:1]([O:3][C:4]1[C:5]([O:23][CH3:24])=[CH:6][C:7]2[O:12][C:11](=[O:13])[C:10]([CH2:14][CH2:15]OS(C)(=O)=O)=[C:9]([CH3:21])[C:8]=2[CH:22]=1)[CH3:2].[CH3:25][O:26][C:27]1[CH:32]=[CH:31][CH:30]=[CH:29][C:28]=1[N:33]1[CH2:38][CH2:37][NH:36][CH2:35][CH2:34]1>C(O)C.C(Cl)(Cl)Cl>[CH2:1]([O:3][C:4]1[C:5]([O:23][CH3:24])=[CH:6][C:7]2[O:12][C:11](=[O:13])[C:10]([CH2:14][CH2:15][N:36]3[CH2:35][CH2:34][N:33]([C:28]4[CH:29]=[CH:30][CH:31]=[CH:32][C:27]=4[O:26][CH3:25])[CH2:38][CH2:37]3)=[C:9]([CH3:21])[C:8]=2[CH:22]=1)[CH3:2]

Participants

4

Reactant 2

HCID 13461-(2-Methoxyphenyl)piperazineHCID 19428145HCID 19428145, compound

Product 1

HCID 19428156HCID 19428156, compoundYield 54%

Reagents, catalysts & solvents 1

HCID 21889567Chloroform ethanolSolvent

Procedure

Process A; starting materials: 6-ethoxy-3-[2-(methanesulphonyloxy)ethyl]-7-methoxy-4-methyl-2H-1-benzopyran-2-one (Example 29) and 1-(2-methoxyphenyl)piperazine; yield 54%; m.p. 143°-145° C. (from ethanol/chloroform).

Sources & evidence

ORD record
ord-059fdfd5367d406392342d1869b10d37
Source dataset
uspto-grants-1996_08
Patent number
US05550129

Reaction notes

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