HuagongsheHuagongshe Chemistry Print Report · For research reference only
1-Phenylpiperazine → 5,6,7-trimethoxy-4-methyl-3-[2-(4-phenyl-1-piperazinyl)ethyl]-2H-1-benzopyran-2-one
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1-Phenylpiperazine | HCID 7096 | — |
| Reactant | 3-[2-(methanesulphonyloxy)ethyl]-5,6,7-trimethoxy-4-methyl-2H-1-benzopyran-2-one | HCID 19428166 | — |
| Solvent | TBME isopropanol | HCID 86616950 | — |
| Product | 5,6,7-trimethoxy-4-methyl-3-[2-(4-phenyl-1-piperazinyl)ethyl]-2H-1-benzopyran-2-one | HCID 19428127 | 49% |
Reaction Steps
Process B; starting materials: 3-[2-(methanesulphonyloxy)ethyl]-5,6,7-trimethoxy-4-methyl-2H-1-benzopyran-2-one (Example 34) and 1-phenylpiperazine; yield 49%; m.p. 136°-137° C. (from TBME/isopropanol).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05550129 |
| Source dataset | uspto-grants-1996_08 |
| ORD ID | ord-8cd34af96ec84c7dbd4a9b49345a84fc |
| Source note | uspto-grants-1996_08 |