Piperazine → HCID 19428503, compound

HRID 1078940Notes

Reaction equation

HRID 1078940 reaction equation
Cl[C:2]1[N:7]=[C:6]([NH:8][C:9]([CH3:12])([CH3:11])[CH3:10])[CH:5]=[C:4]([NH:13][C:14]([CH3:17])([CH3:16])[CH3:15])[N:3]=1.[NH:18]1[CH2:23][CH2:22][NH:21][CH2:20][CH2:19]1>>[CH3:15][C:14]([NH:13][C:4]1[CH:5]=[C:6]([NH:8][C:9]([CH3:12])([CH3:11])[CH3:10])[N:7]=[C:2]([N:18]2[CH2:23][CH2:22][NH:21][CH2:20][CH2:19]2)[N:3]=1)([CH3:17])[CH3:16]

Participants

3

Reactant 2

HCID 4837PiperazineHCID 53704642HCID 53704642, compound

Product 1

HCID 19428503HCID 19428503, compoundYield 76.5%

Procedure

By reacting 2-chloro-4,6-bis(1,1-dimethylethylamino) -pyrimidine with piperazine as described in Example 4, the title product is obtained in a yield of 76.5%, m.p.: 135°-138° C.

Sources & evidence

ORD record
ord-a537099447af464e9bd611576bad5858
Source dataset
uspto-grants-1996_08
Patent number
US05550240

Reaction notes

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