Pyrrolidine → HCID 19428532, compound

HRID 1078947Notes

Reaction equation

HRID 1078947 reaction equation
Cl[C:2]1[N:7]=[C:6]([Cl:8])[CH:5]=[C:4]([NH:9][C:10]([CH3:13])([CH3:12])[CH3:11])[N:3]=1.[NH:14]1[CH2:18][CH2:17][CH2:16][CH2:15]1>>[Cl:8][C:6]1[CH:5]=[C:4]([NH:9][C:10]([CH3:13])([CH3:12])[CH3:11])[N:3]=[C:2]([N:14]2[CH2:18][CH2:17][CH2:16][CH2:15]2)[N:7]=1

Participants

3

Reactant 2

HCID 31268PyrrolidineHCID 19428522HCID 19428522, compound

Product 1

HCID 19428532HCID 19428532, compoundYield 73.8%

Procedure

By reacting 2,4-dichloro-6-(1,1-dimethylethylamino)pyrimidine with pyrrolidine as described in Example 12, the title product is obtained in a yield of 73.8%, m.p.: 148°-150° C.

Sources & evidence

ORD record
ord-ff6809f4ee3540ef8347c1837a072b5b
Source dataset
uspto-grants-1996_08
Patent number
US05550240

Reaction notes

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