Pyrrolidine → HCID 19428500, compound

HRID 1078957Notes

Reaction equation

HRID 1078957 reaction equation
[C:1]12([NH:11][C:12]3[N:17]=[C:16]([Cl:18])[CH:15]=[C:14](Cl)[N:13]=3)[CH2:10][CH:5]3[CH2:6][CH:7]([CH2:9][CH:3]([CH2:4]3)[CH2:2]1)[CH2:8]2.[NH:20]1[CH2:24][CH2:23][CH2:22][CH2:21]1>>[C:1]12([NH:11][C:12]3[N:17]=[C:16]([Cl:18])[CH:15]=[C:14]([N:20]4[CH2:24][CH2:23][CH2:22][CH2:21]4)[N:13]=3)[CH2:10][CH:5]3[CH2:6][CH:7]([CH2:9][CH:3]([CH2:4]3)[CH2:2]1)[CH2:8]2

Participants

3

Reactant 2

HCID 31268PyrrolidineHCID 19428536HCID 19428536, compound

Product 1

HCID 19428500HCID 19428500, compoundYield 86%

Procedure

By reacting 2-(1-adamantylamino)-4,6-dichloropyrimidine with pyrrolidine as described in Example 12, the title compound is obtained in a yield of 86%, m.p.: 178°-180° C.

Sources & evidence

ORD record
ord-5f2309ab40bd42a78171fa6ee1c82ccf
Source dataset
uspto-grants-1996_08
Patent number
US05550240

Reaction notes

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