Urea → 4-Nitrobenzamide

Participants

Reaction Steps

334 g (2.0 mol) of 4-nitrobenzoic acid, 120 g (2.0 mol) of urea and 2.0 g of phosphorous acid are heated in 1000 ml of the organic mother liquor from the preceding experiment, with stirring, at from 158° to 163° C. The mixture is worked up as described above. 313.4 g of 4-nitrobenzamide are obtained having a melting point of from 192° to 195° C. This corresponds to a yield of 94.4% of theory. By acidification of the aqueous mother liquor to pH 2, 8.8 g of 4-nitrobenzoic acid (2.6% of theory) are obtained.

Provenance & Evidence