Diisopropyl Ether → HCID 23367111, compound

HRID 1079465Notes

Reaction equation

HRID 1079465 reaction equation
[CH3:1][C:2]1[O:6][N:5]=[C:4]([O:7][CH2:8][C:9]([OH:11])=O)[C:3]=1[Br:12].[N+]([O-])(O)=O.[O:17]([CH2:21][CH2:22][NH2:23])[N+:18]([O-:20])=[O:19].C(OC(C)C)(C)C>>[O:17]([CH2:21][CH2:22][NH:23][C:9](=[O:11])[CH2:8][O:7][C:4]1[C:3]([Br:12])=[C:2]([CH3:1])[O:6][N:5]=1)[N+:18]([O-:20])=[O:19]

Participants

4

Reactant 3

HCID 7914Diisopropyl EtherHCID 78397Ethanol, 2-amino-, 1-nitrate, nitrate (1:1)HCID 13051010HCID 13051010, compound

Product 1

HCID 23367111HCID 23367111, compoundYield 40.9%

Procedure

Following a similar treatment to that in Example 2 and using 472 mg of 5-methyl-4-bromo-3-isoxazolyloxyacetic acid and 338 mg of nitroxyethylamine nitrate, 265 mg of the title compound was obtained as colorless needles (solvent for recrystallization; diisopropyl ether).

Sources & evidence

ORD record
ord-05659cdb8c0b4e6b84614d423d55ba64
Source dataset
uspto-grants-1996_12
Patent number
US05580893

Reaction notes

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