Acetone → HCID 23367237, compound

To a solution of 2-methylthiazoline (10.1 g) in dioxane (20 ml) was added 2-bromoethanol (13.8 g), and the mixture was heated under reflux for about 6 hours. After cooling the reaction, acetone (30 ml) and ether (130 ml) were added with stirring, and the resulting mixture was left standing. After the pale brown supernatant was discarded, ether (150 ml) was further added to the amorphous precipitate thus obtained. The mixture was stirred and left standing. Supernatant obtained was discarded, and the viscous precipitates obtained was left standing at an ambient temperature under reduced pressure to give the title compound as the yellow amorphous residue.

1. temperaturethe mixture was heated
2. temperatureunder reflux for about 6 hours
3. temperatureAfter cooling
4. additionwere added
5. waitthe resulting mixture was left
6. customthus obtained
7. stirringThe mixture was stirred
8. waitleft
9. customSupernatant obtained
10. customthe viscous precipitates
11. customobtained
12. waitwas left
13. customstanding at an ambient temperature under reduced pressure

ORD record

ord-d8ac449be7624aadaab34d52356f45f4

Source dataset

uspto-grants-1996_12

DOI

10.6084/m9.figshare.5104873.v1

Patent number

US05580904