Hydrogen Bromide → HCID 23367254, compound

HRID 1080227Notes

Reaction equation

HRID 1080227 reaction equation
C[O:2][C:3]1[CH:4]=[C:5]([C:20]([OH:22])=[O:21])[C:6]([C:9]2[C:10](=[CH:14][C:15]([O:18]C)=[CH:16][CH:17]=2)[C:11]([OH:13])=[O:12])=[CH:7][CH:8]=1.Br>C(O)(=O)C>[OH:2][C:3]1[CH:4]=[C:5]([C:20]([OH:22])=[O:21])[C:6]([C:9]2[C:10](=[CH:14][C:15]([OH:18])=[CH:16][CH:17]=2)[C:11]([OH:13])=[O:12])=[CH:7][CH:8]=1

Participants

4

Reactant 2

HCID 260Hydrogen BromideHCID 233672564,4'-Dimethoxy[1,1'-biphenyl]-2,2'-dicarboxylic acid

Product 1

HCID 23367254HCID 23367254, compoundYield 91.2%

Reagents, catalysts & solvents 1

HCID 176Acetic AcidSolvent

Procedure

The following reactants, 9.06 g of 4,4'-dimethoxydiphenic acid, 100 ml of glacial acetic acid and 50 g of 48% HBr were heated at reflux for 12 hours. After most of the solvent had been distilled off, water was added and the solution heated to dissolve the solid residue. The solution was decolorized twice using active charcoal and cooled to yield 7.5 g of white 4,4'-dihydroxydiphenic acid.

Workup

  1. temperatureat reflux for 12 hours
  2. distillationAfter most of the solvent had been distilled off
  3. additionwater was added
  4. temperaturethe solution heated
  5. dissolutionto dissolve the solid residue
  6. temperaturecooled

Sources & evidence

ORD record
ord-51a6b3ecc9114c218571af10bf9fd61f
Source dataset
uspto-grants-1996_12
Patent number
US05580950

Reaction notes

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