Potassium Carbonate → HCID 23365529, compound

HRID 1080673Notes

Reaction equation

HRID 1080673 reaction equation
[Cl:1][C:2]1[N:10]=[C:9]2[C:5]([NH:6][CH:7]=[N:8]2)=[C:4]([Cl:11])[N:3]=1.C(=O)([O-])[O-].[K+].[K+].Br[CH:19]([C:21]1[CH:26]=[CH:25][CH:24]=[CH:23][CH:22]=1)[CH3:20]>>[Cl:1][C:2]1[N:10]=[C:9]2[C:5]([N:6]([CH:19]([C:21]3[CH:26]=[CH:25][CH:24]=[CH:23][CH:22]=3)[CH3:20])[CH:7]=[N:8]2)=[C:4]([Cl:11])[N:3]=1.[Cl:1][C:2]1[N:10]=[C:9]2[C:5]([N:6]=[CH:7][N:8]2[CH:19]([C:21]2[CH:26]=[CH:25][CH:24]=[CH:23][CH:22]=2)[CH3:20])=[C:4]([Cl:11])[N:3]=1

Participants

5

Reactant 3

HCID 11430Potassium CarbonateHCID 11454(1-Bromoethyl)benzeneHCID 53244122,6-Dichloropurine

Product 2

HCID 23365529HCID 23365529, compoundHCID 23365535HCID 23365535, compound

Procedure

Using the same general procedure of Preparation A, 4.12 g of 2,6-dichloropurine, 3.32 g of potassium carbonate and 4.44 g of 1-bromoethylbenzene gave 830 mg of 2,6-dichloro-7-(1-phenylethyl)purine and 1.3 g of 2,6-dichloro-9-(1-phenylethyl)purine.

Sources & evidence

ORD record
ord-3d85eaac0d564bebb43557779cd79129
Source dataset
uspto-grants-1996_12
Patent number
US05583137

Reaction notes

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