Octylamine → HCID 22283721, compound

HRID 1081218Notes

Reaction equation

HRID 1081218 reaction equation
[CH2:1]([NH2:9])[CH2:2][CH2:3][CH2:4][CH2:5][CH2:6][CH2:7][CH3:8].[OH:10][C:11]1[C:12]([CH3:21])=[CH:13][C:14]2[O:18][C:17](=[O:19])[CH2:16][C:15]=2[CH:20]=1>CN(C)C=O>[CH2:1]([NH:9][C:17](=[O:19])[CH2:16][C:15]1[CH:20]=[C:11]([OH:10])[C:12]([CH3:21])=[CH:13][C:14]=1[OH:18])[CH2:2][CH2:3][CH2:4][CH2:5][CH2:6][CH2:7][CH3:8]

Participants

4

Reactant 2

HCID 8143OctylamineHCID 22910794HCID 22910794, compound

Product 1

HCID 22283721HCID 22283721, compound

Reagents, catalysts & solvents 1

HCID 6228DimethylformamideSolvent2×

Procedure

A solution of 7.75 g of n-octylamine dissolved in 15 ml of dimethylformamide is placed in a solution of 10 g of 5-hydroxy-6-methyl-3H-benzofuran-2-one dissolved in 15 ml of dimethylformamide. After 15 minutes at 100° C., the mixture is evaporated to dryness at reduced pressure. It is treated with 100 ml of ethyl acetate, rinsed with water, dried, then evaporated, yielding a white solid which is recrystallized from isopropyl acetate.

Workup

  1. customthe mixture is evaporated to dryness at reduced pressure
  2. additionIt is treated with 100 ml of ethyl acetate
  3. washrinsed with water
  4. customdried
  5. customevaporated
  6. customyielding a white solid which
  7. customis recrystallized from isopropyl acetate

Sources & evidence

ORD record
ord-a4f990f9b44d45fda08ab7de70e8f82f
Source dataset
uspto-grants-1996_12
Patent number
US05585105

Reaction notes

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