HuagongsheHuagongshe Chemistry Print Report · For research reference only
HCID 10578293, compound → HCID 10459957, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | HCID 10578293 | HCID 10578293 | — |
| Catalyst | Palladium | HCID 23938 | — |
| Solvent | Methanol | HCID 887 | — |
| Product | HCID 10459957 | HCID 10459957 | 69.5% |
Reaction Steps
In methanol (8 ml) was dissolved N-[3,5-bis (trifluoromethyl)benzyl]-8-(4-fluorophenyl]-5,6-dihydro-N, 6-dimethyl-5-oxo-7-pyrido[4,3-b]pyridinecarboxamide (Example 19) (50 mg). To the solution was added 10% Pd-C (50% hydrous) (40 mg). The mixture was stirred for 3 hours at room temperature under hydrogen atmosphere. The catalyst was filtered off. From the filtrate, the solvent was distilled off to give the above-titled compound as colorless crystals (35 mg).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05585385 |
| Source dataset | uspto-grants-1996_12 |
| ORD ID | ord-92703f3fb00944fa866eab531ae489fd |
| Source note | uspto-grants-1996_12 |