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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1081315Generated: November 2, 2026

HCID 10578293, compound → HCID 10459957, compound

https://huagongshe.com/reaction/1081315

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHCID 10578293HCID 10578293—
CatalystPalladiumHCID 23938—
SolventMethanolHCID 887—
ProductHCID 10459957HCID 1045995769.5%

Reaction Steps

In methanol (8 ml) was dissolved N-[3,5-bis (trifluoromethyl)benzyl]-8-(4-fluorophenyl]-5,6-dihydro-N, 6-dimethyl-5-oxo-7-pyrido[4,3-b]pyridinecarboxamide (Example 19) (50 mg). To the solution was added 10% Pd-C (50% hydrous) (40 mg). The mixture was stirred for 3 hours at room temperature under hydrogen atmosphere. The catalyst was filtered off. From the filtrate, the solvent was distilled off to give the above-titled compound as colorless crystals (35 mg).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS05585385
Source datasetuspto-grants-1996_12
ORD IDord-92703f3fb00944fa866eab531ae489fd
Source noteuspto-grants-1996_12