HCID 54506134, compound → HCID 10780548, compound

HRID 1081332Notes

Reaction equation

HRID 1081332 reaction equation
C([O:3][C:4]([C:6]1[N:11]([CH3:12])[C:10](=[O:13])[C:9]2SC=N[C:8]=2[C:7]=1[C:17]1[CH:22]=[CH:21][C:20]([F:23])=[CH:19][CH:18]=1)=[O:5])C>OS(O)(=O)=O>[F:23][C:20]1[CH:19]=[CH:18][C:17]([C:7]2[C:8]3[CH:9]=[CH:10][N:11]([CH3:6])[C:9]=3[C:10](=[O:13])[N:11]([CH3:12])[C:6]=2[C:4]([OH:3])=[O:5])=[CH:22][CH:21]=1

Participants

3

Reactant 1

HCID 54506134HCID 54506134, compound

Product 1

HCID 10780548HCID 10780548, compound

Reagents, catalysts & solvents 1

HCID 1118Sulfuric AcidSolvent

Procedure

7-(4-Fluorophenyl)-4,5-dihydro-5-methyl-4-oxo-6-thiazolo[5,4-c]pyridinecarboxylic acid ethyl ester obtained in Step 3 was subjected to hydrolysis in 70% H2SO4 at temperatures ranging from 120° to 130° C. to give the above-titled compound as colorless crystals.

Workup

  1. customranging from 120° to 130° C.

Sources & evidence

ORD record
ord-0e976e389feb4a52aa08463152444f7f
Source dataset
uspto-grants-1996_12
Patent number
US05585385

Reaction notes

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