thieno[2,3-c]furan-4,6-dione → 3-(2-Methylbenzoyl)-2-thiophenecarboxylic acid

HRID 1081334Notes

Reaction equation

HRID 1081334 reaction equation
[S:1]1[CH:5]=[CH:4][C:3]2[C:6]([O:8][C:9](=[O:10])[C:2]1=2)=[O:7].[CH3:11][C:12]1[CH:17]=[CH:16][CH:15]=[CH:14][C:13]=1[Mg]Br>C1COCC1>[CH3:11][C:12]1[CH:17]=[CH:16][CH:15]=[CH:14][C:13]=1[C:6]([C:3]1[CH:4]=[CH:5][S:1][C:2]=1[C:9]([OH:8])=[O:10])=[O:7]

Participants

4

Reactant 2

HCID 222951thieno[2,3-c]furan-4,6-dioneHCID 178424303HCID 178424303, compound

Product 1

HCID 233640543-(2-Methylbenzoyl)-2-thiophenecarboxylic acid

Reagents, catalysts & solvents 1

HCID 8028TetrahydrofuranSolvent

Procedure

2,3-Thiophenedicarboxylic anhydride was allowed to react with 2-methylphenyl magnesium bromide in THF, and the reaction mixture was processed to give 3-(2-methylbenzoyl)-2-thiophenecarboxylic acid as colorless crystals.

Sources & evidence

ORD record
ord-b3fd19d962724aeda8e7836ae374750a
Source dataset
uspto-grants-1996_12
Patent number
US05585385

Reaction notes

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