HuagongsheHuagongshe Chemistry Print Report · For research reference only
Piperidine → Piperidine-1-sulfonyl chloride
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Piperidine | HCID 8082 | — |
| Reactant | Sulfuryl chloride | HCID 24648 | — |
| Product | Piperidine-1-sulfonyl chloride | HCID 11298344 | — |
Reaction Steps
A solution of 4 g of sulfuryl chloride in acetronitrile was treated dropwise with 861 mg of piperidine at ambient temperature under an atmosphere of nitrogen. After complete addition, the mixture was refluxed for 18 h, cooled to room temperature and concentrated in vacuo to yield the title product as a red oil. TLC: Rf=0.86, CH2Cl2. (1H)-NMR (CDCl3) consistent with structure.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05585397 |
| Source dataset | uspto-grants-1996_12 |
| ORD ID | ord-8c899d8117df4bb1941b0a238fa9cbe2 |
| Source note | uspto-grants-1996_12 |