Piperidine → HCID 15231557, compound

Participants

Reaction Steps

2 ml of piperidine were added to a solution of 500 mg of the compound obtained in Example 16 step A) in 25 ml of DCM. The reaction mixture was then stirred for 18 hours at room temperature. It was concentrated to dryness and the resulting product was passed over silica using DCM and then a DCM/AcOEt mixture (95/5; v/v) as the eluent to give 0.36 g of the expected product in the form of white crystals. M.p. =232° C.

Provenance & Evidence