2-Methoxy-4-nitrobenzenesulfonyl chloride → HCID 23364265, compound

HRID 1081500Notes

Reaction equation

HRID 1081500 reaction equation
[CH2:1]([O:3][C:4]1[CH:19]=[CH:18][C:7]2[NH:8][C:9](=[O:17])[N:10]([C:11]3[CH:16]=[CH:15][CH:14]=[CH:13][N:12]=3)[C:6]=2[CH:5]=1)[CH3:2].[CH3:20][O:21][C:22]1[CH:27]=[C:26]([N+:28]([O-:30])=[O:29])[CH:25]=[CH:24][C:23]=1[S:31](Cl)(=[O:33])=[O:32]>>[CH2:1]([O:3][C:4]1[CH:19]=[CH:18][C:7]2[N:8]([S:31]([C:23]3[CH:24]=[CH:25][C:26]([N+:28]([O-:30])=[O:29])=[CH:27][C:22]=3[O:21][CH3:20])(=[O:32])=[O:33])[C:9](=[O:17])[N:10]([C:11]3[CH:16]=[CH:15][CH:14]=[CH:13][N:12]=3)[C:6]=2[CH:5]=1)[CH3:2]

Participants

3

Reactant 2

HCID 3094582-Methoxy-4-nitrobenzenesulfonyl chlorideHCID 54505929HCID 54505929, compound

Product 1

HCID 23364265HCID 23364265, compoundYield 65.1%

Procedure

This compound is prepared by the procedure described in EXAMPLE 37 step A) starting from 1 g of 5- ethoxy-1,3-dihydro-3-(pyrid-2-yl)-2H-benzimidazol-2-one and 1.2 g of 2-methoxy-4-nitrobenzenesulfonyl chloride. 1.2 g of the expected product are obtained after crystallization from iso ether. M.p.=175° C.

Workup

  1. customThis compound is prepared by the procedure

Sources & evidence

ORD record
ord-5afa97fde1ab4f49a413e80c6d0035ef
Source dataset
uspto-grants-1996_12
Patent number
US05585394

Reaction notes

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