Ammonium formate → HCID 23362662, compound

Participants

Reaction Conditions

Reaction Steps

3,5-Bis-aminomethyl-4-benzylmorpholine (1.3 g, 5.5 mmol) was dissolved in methanol (50 ml). Ammonium-formiate (1.4 g, 22 mmol) and palladium on activated carbon (10%, 5 g) were added. The reaction mixture was stirred at 50° C. under nitrogen for 3 hours. The catalyst was then filtered off and washed with several small portions of methanol and the solution evaporated to dryness. The tri-amine was used direcly in the next reaction step. FAB/MS: 146 (M+1).

Provenance & Evidence