Salicyl Alcohol → HCID 3849418, compound

HRID 1081869Notes

Reaction equation

HRID 1081869 reaction equation
O[CH2:2][C:3]1[CH:8]=[CH:7][CH:6]=[CH:5][C:4]=1[OH:9].[NH:10]1[CH:14]=[N:13][CH:12]=[N:11]1>>[N:10]1([CH2:2][C:3]2[CH:8]=[CH:7][CH:6]=[CH:5][C:4]=2[OH:9])[CH:14]=[N:13][CH:12]=[N:11]1

Participants

3

Reactant 2

HCID 5146Salicyl AlcoholHCID 92571H-1,2,4-Triazole

Product 1

HCID 3849418HCID 3849418, compoundYield 76%

Conditions

Temperature
160 °C

Procedure

The mixture of 2-hydroxymethylphenol (25.3 g) and 1H-1,2,4-triazole (15.5 g) was agitated at about 160° C. for 1 hour. After left to stand for cooling, the mixture was solidified into crystal, which was then recrystallized from ethanol and collected to give the title compound (27 g; 76 %).

Workup

  1. waitAfter left
  2. temperaturefor cooling
  3. customwas then recrystallized from ethanol
  4. customcollected

Sources & evidence

ORD record
ord-bf3853308ec64551a810bae3e216525d
Source dataset
uspto-grants-1996_12
Patent number
US05587392

Reaction notes

Loading…