2,5,8,11,14,17,20-Heptaoxadocosan-22-amine → N-[3,6,9,12,15,18,21-heptaoxadocos-1-y1]-2,3,4,5-tetraiodopyrrol-1-acetamide

HRID 1081953Notes

Reaction equation

HRID 1081953 reaction equation
C(O[C:4](=[O:15])[CH2:5][N:6]1[C:10]([I:11])=[C:9]([I:12])[C:8]([I:13])=[C:7]1[I:14])C.[CH2:16]([NH2:38])[CH2:17][O:18][CH2:19][CH2:20][O:21][CH2:22][CH2:23][O:24][CH2:25][CH2:26][O:27][CH2:28][CH2:29][O:30][CH2:31][CH2:32][O:33][CH2:34][CH2:35][O:36][CH3:37]>>[CH2:16]([NH:38][C:4](=[O:15])[CH2:5][N:6]1[C:7]([I:14])=[C:8]([I:13])[C:9]([I:12])=[C:10]1[I:11])[CH2:17][O:18][CH2:19][CH2:20][O:21][CH2:22][CH2:23][O:24][CH2:25][CH2:26][O:27][CH2:28][CH2:29][O:30][CH2:31][CH2:32][O:33][CH2:34][CH2:35][O:36][CH3:37]

Participants

3

Reactant 2

HCID 187646512,5,8,11,14,17,20-Heptaoxadocosan-22-amineHCID 539447922,3,4,5-Tetraiodopyrrol-1-acetic acid ethyl ester

Product 1

HCID 23363352N-[3,6,9,12,15,18,21-heptaoxadocos-1-y1]-2,3,4,5-tetraiodopyrrol-1-acetamideYield 114.2%

Procedure

According to the procedure described in Ex. 2, 2.3 g of 2,3,4,5-tetraiodopyrrol-1-acetic acid ethyl ester (prepared according to the procedure described in Ex. 1) (0.00457 mol) and 23.27 g of compound B, 3,6,9,12,15,18,21-heptaoxadocosylamine, (0.0685 mol) are reacted. 3.82 g of N-[3,6,9,12,15,18,21-heptaoxadocos-1-y1]-2,3,4,5-tetraiodopyrrol-1-acetamide (0.0040 mol) are obtained.

Sources & evidence

ORD record
ord-c4f9e4cc5bd54f3da58656d69a4609a1
Source dataset
uspto-grants-1996_12
Patent number
US05587487

Reaction notes

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