Dichloromethane → 1-(Cyclopropylmethyl)-3-[4-[4-[[4-(1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-yl)phenyl]methyl]-2-methylpiperazine-1-carbonyl]phenyl]urea
Reaction equation
[CH2:49]([P:50]([OH:51])(=[O:52])[OH:53])[CH2:54][CH3:55].[CH3:42][CH2:43][N:44]([CH2:45][CH3:46])[CH2:47][CH3:48].[CH:25]1([CH2:28][NH:29][C:30]([NH:31][c:32]2[cH:33][cH:34][c:35]([C:36](=[O:37])[OH:38])[cH:39][cH:40]2)=[O:41])[CH2:26][CH2:27]1.[Cl:56][CH2:57][Cl:58].[F:1][C:2]([C:3]([C:4]([F:5])([F:6])[F:7])([OH:8])[c:9]1[cH:10][cH:11][c:12]([CH2:15][N:16]2[CH2:17][CH:18]([CH3:22])[NH:19][CH2:20][CH2:21]2)[cH:13][cH:14]1)([F:23])[F:24]>>[F:1][C:2]([C:3]([C:4]([F:5])([F:6])[F:7])([OH:8])[c:9]1[cH:10][cH:11][c:12]([CH2:15][N:16]2[CH2:17][CH:18]([CH3:22])[N:19]([C:36]([c:35]3[cH:34][cH:33][c:32]([NH:31][C:30]([NH:29][CH2:28][CH:25]4[CH2:26][CH2:27]4)=[O:41])[cH:40][cH:39]3)=[O:37])[CH2:20][CH2:21]2)[cH:13][cH:14]1)([F:23])[F:24]Participants
6
Reactant 5
Product 1
Sources & evidence
- ORD record
- ord-08db09341edf4f4fb46068d30abe2d5a
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (2/10)
Reaction notes
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