Hydrochloric Acid → HCID 23362031, compound

HRID 1082051Notes

Reaction equation

HRID 1082051 reaction equation
[N+:1]([C:4]1[CH:9]=[CH:8][CH:7]=[C:6]([N+:10]([O-])=O)[C:5]=1[NH:13][CH2:14][CH2:15][OH:16])([O-])=O.[OH-].[Na+].[ClH:19]>>[ClH:19].[ClH:19].[NH2:1][C:4]1[CH:9]=[CH:8][CH:7]=[C:6]([NH2:10])[C:5]=1[NH:13][CH2:14][CH2:15][OH:16]

Participants

4

Reactant 3

HCID 313Hydrochloric AcidHCID 14798Sodium HydroxideHCID 233620182-(2,6-Dinitroanilino)ethan-1-ol

Product 1

HCID 23362031HCID 23362031, compound

Conditions

Temperature
80 °C

Procedure

18.3 g (0.0805 mol) of 2-[(2,6-dinitrophenyl)amino]ethanol in a solution containing 144 g of stannous chloride dihydrate in 146 ml of a concentrated hydrochloric acid solution are heated at 80° C. in an oil bath for 15 minutes. The reaction mixture is cooled in an ice bath, 460 ml of a concentrated sodium hydroxide solution are slowly added and then extraction is carried out three times with dichloromethane. The organic phases are combined, are dried and evaporated to dryness.

Workup

  1. temperatureThe reaction mixture is cooled in an ice bath
  2. extractionextraction
  3. customare dried
  4. customevaporated to dryness

Sources & evidence

ORD record
ord-fc1f6b8021ed4cb0a15d8ae7d8496d08
Source dataset
uspto-grants-1996_12
Patent number
US05589476

Reaction notes

Loading…