Water → 3,4,8,9-Tetrahydro-6-methoxy-3,3,8,8-tetramethyl-1-phenyl-5-furo[2,3-h]isoquinolineacetonitrile
Reaction equation
[Br:4][CH2:5][c:6]1[c:7]2[c:12]([c:13]3[c:14]([c:15]1[O:16][CH3:17])[O:18][C:19]([CH3:21])([CH3:22])[CH2:20]3)[C:11]([c:23]1[cH:24][cH:25][cH:26][cH:27][cH:28]1)=[N:10][C:9]([CH3:29])([CH3:30])[CH2:8]2.[CH3:32][N:33]([CH3:34])[CH:35]=[O:36].[K:1][C:2]#[N:3].[OH2:31]>>[C:2](#[N:3])[CH2:5][c:6]1[c:7]2[c:12]([c:13]3[c:14]([c:15]1[O:16][CH3:17])[O:18][C:19]([CH3:21])([CH3:22])[CH2:20]3)[C:11]([c:23]1[cH:24][cH:25][cH:26][cH:27][cH:28]1)=[N:10][C:9]([CH3:29])([CH3:30])[CH2:8]2Participants
5
Reactant 4
Product 1
Sources & evidence
- ORD record
- ord-e1e850162ae54447a2b6014b40df7d3c
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (2/10)
Reaction notes
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