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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1083168Generated: November 2, 2026

Benzofuran, 5-bromo- → HCID 178506399, compound

https://huagongshe.com/reaction/1083168

Reaction equation

Participants

RoleNameHCIDCharge
ReactantBenzofuran, 5-bromo-HCID 90015—
Reactant1-(Difluoromethyl)-2-phenyl-1H-imidazoleHCID 53485766—
ReagentPotassium TrimethylacetateHCID 23662159—
CatalystTris[3,5-bis(trifluoromethyl)phenyl]phosphineHCID 2778032—
CatalystHCID 178455864HCID 178455864—
SolventDimethylacetamideHCID 31374—
ProductHCID 178506399HCID 17850639974.77%
Internal standard4,4'-Bis(1,1-dimethylethyl)-1,1'-biphenylHCID 74195—

Reaction Conditions

Temperature120 °C

Provenance & Evidence

DOI10.26434/chemrxiv
Source datasetPd-catalyzed C-H arylation of imidazole with aryl bromide
ORD IDord-4538a1d2c9554e60b1cfa21328aab720
Source notePd-catalyzed C-H arylation of imidazole with aryl bromide