Dichloromethane → 1-(4-((1H-Benzo[d]imidazol-2-yl)methyl)benzoyl)pyrrolidin-3-yl Methanesulfonate

HRID 108450Notes

Reaction equation

HRID 108450 reaction equation
[CH3:34][S:35]([Cl:36])(=[O:37])=[O:38].[CH:25]([N:26]([CH:27]([CH3:28])[CH3:29])[CH2:30][CH3:31])([CH3:32])[CH3:33].[Cl:39][CH2:40][Cl:41].[nH:1]1[c:2]([CH2:10][c:11]2[cH:12][cH:13][c:14]([C:17](=[O:18])[N:19]3[CH2:20][CH:21]([OH:24])[CH2:22][CH2:23]3)[cH:15][cH:16]2)[n:3][c:4]2[c:5]1[cH:6][cH:7][cH:8][cH:9]2>>[n:1]1[c:2]([CH2:10][c:11]2[cH:12][cH:13][c:14]([C:17](=[O:18])[N:19]3[CH2:20][CH:21]([O:24][S:35]([CH3:34])(=[O:37])=[O:38])[CH2:22][CH2:23]3)[cH:15][cH:16]2)[nH:3][c:4]2[c:5]1[cH:6][cH:7][cH:8][cH:9]2

Participants

5

Reactant 4

HCID 6344DichloromethaneHCID 31297Methanesulfonyl chlorideHCID 81531DiisopropylethylamineHCID 68426533[4-(1H-benzoimidazol-2-ylmethyl)-phenyl]-(3-hydroxy-pyrrolidin-1-yl)-methanone

Product 1

HCID 866152161-(4-((1H-Benzo[d]imidazol-2-yl)methyl)benzoyl)pyrrolidin-3-yl Methanesulfonate

Sources & evidence

ORD record
ord-fbca7f3c6e0a4196a92a86e8454a677c
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (2/10)

Reaction notes

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