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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1084708Generated: October 28, 2026

Hydrochloric Acid → HCID 20062527, compound

https://huagongshe.com/reaction/1084708

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHydrochloric AcidHCID 313—
ReactantFormaldehydeHCID 712—
Reactant5,11-dihydro-11-(2-propynyl)-6H-pyrido[2,3-b][1,4]benzodiazepin-6-oneHCID 14552085—
ReactantHCID 20062518HCID 20062518—
ProductHCID 20062527HCID 2006252734%

Reaction Steps

Prepared analogously to Example lb) from 5,11-dihydro-11-(prop-2-ynyl)-6H-pyrido[2,3-b][1,4]benzodiazepin-6-one, paraformaldehyde and 2-[[(cyclohexyl)methylamino]methyl]piperidine in a yield of 34% of theory. The monohydrochloride melted at 205° C. (decomp.).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS05006522
Source datasetuspto-grants-1991_04
ORD IDord-4656e4ef49df4ef5ac01b4343ff5bf35
Source noteuspto-grants-1991_04