反应详情

A solution of 0.61 g (1.8 mmol) of 7-(hydroxyphenylmethyl)-3-methoxymethyl-2-phenyl-6-azabenzo[b]thiophene in 2.7 mL of 2M HCl and 2.7 mL of methanol was heated at reflux for 30 minutes. The solution was cooled and partitioned between ethyl aoetate and water. The ethyl acetate layer was dried and concentrated to afford 0.50 g (93%) of white solid, m.p. 214-215° C.

1. temperatureat reflux for 30 minutes
2. temperatureThe solution was cooled
3. custompartitioned between ethyl aoetate and water
4. dry with materialThe ethyl acetate layer was dried
5. concentrationconcentrated