Isopropyl Acetate → HCID 178479104, compound

HRID 1084783Notes

Reaction equation

HRID 1084783 reaction equation
[ClH:1].C([N:6]([N+:13]1[N-:14][O:15][C:16](=[NH:18])[CH:17]=1)[CH:7]1[CH2:12][CH2:11][CH2:10][CH2:9][CH2:8]1)(C)(C)C.C(OC(C)C)(=O)C>Cl>[ClH:1].[CH:7]1([NH:6][N+:13]2[N-:14][O:15][C:16](=[NH:18])[CH:17]=2)[CH2:8][CH2:9][CH2:10][CH2:11][CH2:12]1

Participants

4

Reactant 2

HCID 7915Isopropyl AcetateHCID 14795574HCID 14795574, compound

Product 1

HCID 178479104HCID 178479104, compound

Reagents, catalysts & solvents 1

HCID 313Hydrochloric AcidSolvent

Procedure

A solution of 4 g of 3-(tert.-butyl-N-cyclohexyl-amino)sydnonimine hydrochloride in 30 ml of concentrated ethanolic hydrochloric acid is left to stand at room temperature for one day and then concentrated in a rotary evaporator. The residue is purified by column chromatography (silica gel, CH2Cl2 :MeOH=9:1) and the residue obtained after concentration of the corresponding fractions is stirred with isopropyl acetate and filtered off with suction. Yield: 2.5 g melting point: 90° C. (decomp.)

Workup

  1. concentrationconcentrated in a rotary evaporator
  2. customThe residue is purified by column chromatography (silica gel, CH2Cl2 :MeOH=9:1)
  3. customthe residue obtained after concentration of the corresponding fractions
  4. filtrationfiltered off with suction

Sources & evidence

ORD record
ord-88ff267ec690421888ffbb83e95012b7
Source dataset
uspto-grants-1991_04
Patent number
US05006540

Reaction notes

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