HuagongsheHuagongshe Chemistry Print Report · For research reference only
Triethylamine → 5-(Dimethylphosphoryl)-3-phenyl-4,5-dihydro-1,2-oxazole
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Triethylamine | HCID 8471 | — |
| Reactant | (Z)-Benzaldehyde oxime | HCID 12143 | — |
| Reactant | Chlorosuccinimide | HCID 31398 | — |
| Reactant | 2180-73-6 | HCID 12943870 | — |
| Product | 5-(Dimethylphosphoryl)-3-phenyl-4,5-dihydro-1,2-oxazole | HCID 3079421 | 57.7% |
Reaction Steps
Preparation is carried out in analogy to Example 1 by starting from 60.6 g (0.5 mol) of benzaldoxime, 73.45 g (0.55 mol) of N-chlorosuccinimide, 57.3 g (0.55 mol) of vinyldimethylphosphine oxide and 76.5 ml (0.55 mol) of triethylamine. After the usual working up, the product is recrystallized from. tert.butyl methyl ether. 64.4 g of pure product of melting point 153° C. are obtained.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05006515 |
| Source dataset | uspto-grants-1991_04 |
| ORD ID | ord-b6549457d173468b816b8214d4c2a375 |
| Source note | uspto-grants-1991_04 |