HuagongsheHuagongshe Chemistry Print Report · For research reference only
Triethylamine → Dimethyl 3(4-nitrophenyl)-2-isoxazolin-5-ylphosphonate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Triethylamine | HCID 8471 | — |
| Reactant | Chlorosuccinimide | HCID 31398 | — |
| Reactant | Dimethyl vinylphosphonate | HCID 78376 | — |
| Reactant | p-Nitrobenzaldoxime | HCID 96339 | — |
| Product | Dimethyl 3(4-nitrophenyl)-2-isoxazolin-5-ylphosphonate | HCID 14460583 | — |
Reaction Steps
Preparation is carried out in analogy to Example 1 from 19.6 g (0.118 mol) of 4-nitrobenzaldoxime, 17.4 g (0.13 mol) of N-chlorosuccinimide, 16.1 g (0.118 mol) of dimethyl vinylphosphonate and 18.7 ml (0.13 mol) of triethylamine. Crystallization of the crude product from tert.butyl methyl ether provides analytically pure compound of melting point 156° to 158° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05006515 |
| Source dataset | uspto-grants-1991_04 |
| ORD ID | ord-86704c721ee24713a97ac5b14f74ef72 |
| Source note | uspto-grants-1991_04 |