3-Chloro-1-propanol → Diisopropylether ethyl acetate

HRID 1084839Notes

Reaction equation

HRID 1084839 reaction equation
[OH:1][C:2]1[CH:7]=CC(N2C3=NC=CC=C3C(C3C=CC=CC=3)=N2)=C[CH:3]=1.Cl[CH2:24][CH2:25][CH2:26][OH:27]>>[C:26]([O:1][CH2:2][CH3:7])(=[O:27])[CH3:25].[CH:25]([O:1][CH:2]([CH3:3])[CH3:7])([CH3:26])[CH3:24]

Participants

3

Reactant 2

HCID 123133-Chloro-1-propanolHCID 14796259HCID 14796259, compound

Product 1

HCID 22281796Diisopropylether ethyl acetate

Procedure

By reacting in the same manner as in Example 1, using 4 g of 1-(4-hydroxyphenyl)-3-phenyl-1H-pyrazolo[3,4-b]pyridine and 3.6 g of 3-chloropropanol and recrystallizing the obtained crude crystals from ethyl acetate-isopropyl ether, there was obtained 1-[4-(3-hydroxypropoxy)phenyl]-3-phenyl-1H-pyrazolo[3,4-b]pyridine, m.p. 135°-138° C.

Workup

  1. customrecrystallizing the

Sources & evidence

ORD record
ord-ac520d75b54f4dbda0a8e1328e94b3d6
Source dataset
uspto-grants-1991_04
Patent number
US05006520

Reaction notes

Loading…