Chlorosulfonic acid → HCID 20062884, compound

HRID 1084938Notes

Reaction equation

HRID 1084938 reaction equation
[Cl:1][S:2]([OH:5])(=O)=[O:3].[CH3:6][O:7][C:8]1[C:13]2[CH2:14][CH:15]([CH3:17])[O:16][C:12]=2[C:11]([C:18]([OH:20])=[O:19])=[CH:10][CH:9]=1>>[Cl:1][S:2]([C:9]1[CH:10]=[C:11]([C:18]([OH:20])=[O:19])[C:12]2[O:16][CH:15]([CH3:17])[CH2:14][C:13]=2[C:8]=1[O:7][CH3:6])(=[O:5])=[O:3]

Participants

3

Reactant 2

HCID 24638Chlorosulfonic acidHCID 14838687HCID 14838687, compound

Product 1

HCID 20062884HCID 20062884, compound

Conditions

Temperature
50 °C

Procedure

218 g of chlorosulphonic acid were introduced into a 500 ml round-bottomed flask and 65 g of finely ground 4-methoxy-2-methyl-2,3-dihydrobenzofuran-7-carboxylic acid were added in small amounts. The temperature rose to 38° C. The contents were then heated to 50° C. After cooling, the solution obtained was poured, in small amounts, onto ice, with stirring.

Workup

  1. customrose to 38° C
  2. temperatureAfter cooling
  3. customthe solution obtained
  4. additionwas poured, in small amounts, onto ice

Sources & evidence

ORD record
ord-9a97aa7b0c3a40a982a79f6a72f6e42a
Source dataset
uspto-grants-1991_04
Patent number
US05006570

Reaction notes

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