Hydrogen Bromide → HCID 13983558, compound

HRID 1084944Notes

Reaction equation

HRID 1084944 reaction equation
[BrH:1].[OH:2][C:3]1[C:12]([CH2:13][CH:14]=[CH2:15])=[C:11]([NH:16][C:17]([CH3:19])=[O:18])[CH:10]=[CH:9][C:4]=1[C:5]([O:7][CH3:8])=[O:6]>[Hg].O>[OH:2][C:3]1[C:12]([CH2:13][CH2:14][CH2:15][Br:1])=[C:11]([NH:16][C:17]([CH3:19])=[O:18])[CH:10]=[CH:9][C:4]=1[C:5]([O:7][CH3:8])=[O:6]

Participants

5

Reactant 2

HCID 260Hydrogen BromideHCID 10800613Benzoic acid, 4-(acetylamino)-2-hydroxy-3-(2-propenyl)-, methyl ester

Product 1

HCID 13983558HCID 13983558, compound

Reagents, catalysts & solvents 2

HCID 23931MercuryCatalystHCID 962WaterSolvent

Procedure

2277 g of 66% hydrobromic acid and 308 g of methyl 2-hydroxy-3-allyl-4-acetaminobenzoate were introduced into a 3-liter round-bottomed flask equipped with a leakproof stirrer, a thermometer and a safety tube containing mercury so that a pressure of approximately 2 cm of mercury is created in the apparatus. The mixture was stirred for 4 hours and then allowed to stand overnight. 5 liters of water were then added. The precipitate formed was drained, washed with water and dried at 50° C.

Workup

  1. customequipped with a leakproof stirrer
  2. waitto stand overnight
  3. customThe precipitate formed
  4. washwashed with water
  5. customdried at 50° C.

Sources & evidence

ORD record
ord-5d60dcb40c474590b2da9b3f3224ba07
Source dataset
uspto-grants-1991_04
Patent number
US05006570

Reaction notes

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