Hydrochloric Acid → N-[5-[3-(4-Methoxyphenyl)propoxy]pentyl]benzenemethanamine hydrochloride

HRID 1084957노트

반응식

HRID 1084957 반응식
Br[CH2:2][CH2:3][CH2:4][CH2:5][CH2:6][O:7][CH2:8][CH2:9][CH2:10][C:11]1[CH:16]=[CH:15][C:14]([O:17][CH3:18])=[CH:13][CH:12]=1.[CH2:19]([NH2:26])[C:20]1[CH:25]=[CH:24][CH:23]=[CH:22][CH:21]=1.[ClH:27]>O>[ClH:27].[CH3:18][O:17][C:14]1[CH:15]=[CH:16][C:11]([CH2:10][CH2:9][CH2:8][O:7][CH2:6][CH2:5][CH2:4][CH2:3][CH2:2][NH:26][CH2:19][C:20]2[CH:25]=[CH:24][CH:23]=[CH:22][CH:21]=2)=[CH:12][CH:13]=1

참가 물질

5

반응물 3

HCID 313Hydrochloric AcidHCID 7504BenzylamineHCID 197980251-[3-[(5-Bromopentyl)oxy]propyl]-4-methoxybenzene

생성물 1

HCID 20062857N-[5-[3-(4-Methoxyphenyl)propoxy]pentyl]benzenemethanamine hydrochloride

시약·촉매·용매 1

HCID 962Water용매

실험 절차

1-[3-[(5-Bromopentyl)oxy]propyl]-4-methoxybenzene (2.0 g) was added to benzylamine (6 ml) at 120° under nitrogen. The solution was stirred for 2 h at 120° then added (hot) to 2N hydrochloric acid (50 ml) and water (25 ml). The resulting precipitate was collected by filtration, washed with 2N hydrochloric acid, water and ER then dried at 50° under vacuum to give the title compound as a white solid (1.79 g) m.p. 118°-121°.

후처리

  1. filtrationThe resulting precipitate was collected by filtration
  2. washwashed with 2N hydrochloric acid, water and ER
  3. customthen dried at 50° under vacuum

출처 및 근거

ORD 기록
ord-9efbd0bb47ee4b3e938eb09aca5bf8dc
출처 데이터셋
uspto-grants-1991_04
특허 번호
US05006556

반응 노트

불러오는 중…