HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-[[(Ethoxy)(phthalimidomethyl)phosphinyl]methyl]-4-methylvaleric acid → (2-Oxoazacyclotridecan-3-yl)valeramide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-[[(Ethoxy)(phthalimidomethyl)phosphinyl]methyl]-4-methylvaleric acid | HCID 20063016 | — |
| Reactant | (-)-3-Amino-2-azacyclotridecanone | HCID 21939029 | — |
| Product | (2-Oxoazacyclotridecan-3-yl)valeramide | HCID 131716207 | — |
Reaction Steps
In a manner analogous to that describe in Example 1(A)(iv), from 1.9 g of 2(RS)-[[(RS)-(ethoxy)(phthalimidomethyl)phosphinyl]methyl]-4-methylvaleric acid and 1.0 g of (-)-3-amino-2-azacyclotridecanone, there were obtained 2.1 g of 2(RS)-[[(RS)-(ethoxy)(phthalimidomethyl)phosphinyl]methyl]-4-methyl-N(R or S)-(2-oxoazacyclotridecan-3-yl)valeramide in the form of a white solid.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05006651 |
| Source dataset | uspto-grants-1991_04 |
| ORD ID | ord-818fdfd3ca0344ccb2a536f23b681664 |
| Source note | uspto-grants-1991_04 |