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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1085056Generated: November 1, 2026

1-Chloro-2-(diethylamine)ethane hydrochloride → 4(3H)-Quinazolinone, 2-((2-(diethylamino)ethyl)thio)-3-phenyl-

https://huagongshe.com/reaction/1085056

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1-Chloro-2-(diethylamine)ethane hydrochlorideHCID 13363—
ReactantHCID 178515047HCID 178515047—
Product4(3H)-Quinazolinone, 2-((2-(diethylamino)ethyl)thio)-3-phenyl-HCID 6374332.7%

Reaction Steps

The title compound was prepared in a yield of 32.7%, using 2-mercapto-3-phenyl-4(3H)-quinazolinone in place of 3-isobutyl-2-mercapto-4(3H)-quinazoline and β-diethylaminoethyl chloride hydrochloride in place of 2-chloromethylpyridine hydrochloride.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS05008266
Source datasetuspto-grants-1991_04
ORD IDord-e075142c14de418cb611548f5aa51646
Source noteuspto-grants-1991_04