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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1085058Generated: November 4, 2026

2-Chloromethylbenzimidazole → 2-(2-Benzimidazolylmethylthio)-3-phenyl-4(3H)-quinazolinone

https://huagongshe.com/reaction/1085058

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-ChloromethylbenzimidazoleHCID 78571—
ReactantHCID 178515047HCID 178515047—
Product2-(2-Benzimidazolylmethylthio)-3-phenyl-4(3H)-quinazolinoneHCID 1221424539.3%

Reaction Steps

The title compound was prepared in a yield of 39.3%, using 2-mercapto-3-phenyl-4(3H)-quinazolinone in place of 3- isobutyl-2-mercapto-4(3H)-quinazolinone and 2-chloromethylbenzimidazole in place of 2-chloromethylpyridine hydrochloride.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS05008266
Source datasetuspto-grants-1991_04
ORD IDord-b9af2cff4abf438e8dc59d94559db318
Source noteuspto-grants-1991_04