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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1085060Generated: November 1, 2026

2-(Bromomethyl)thiophene → 3-Phenyl-2-(2-thienylmethylthio)-4(3H)-quinazolinone

https://huagongshe.com/reaction/1085060

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-(Bromomethyl)thiopheneHCID 11829978—
ReactantHCID 178515047HCID 178515047—
Product3-Phenyl-2-(2-thienylmethylthio)-4(3H)-quinazolinoneHCID 1457515737.4%

Reaction Steps

The title compound was prepared in a yield of 37.4%, using 2-mercapto-3-phenyl-4(3H)-quinazolinone in place of 3- isobutyl-2-mercapto-4(3H)-quinazolinone and 2-bromomethylthiophene in place of 2-chloromethylpyridine hydrochloride.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS05008266
Source datasetuspto-grants-1991_04
ORD IDord-dea8eee5e0fb4f94927724d9239bced9
Source noteuspto-grants-1991_04