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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1085063Generated: October 31, 2026

2-(Chloromethyl)-4-methoxy-5-methylpyridine → 2-[(4-Methoxy-5-methylpyridin-2-yl)methylthio]-3-phenyl4(3H)-quinazolinone

https://huagongshe.com/reaction/1085063

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-(Chloromethyl)-4-methoxy-5-methylpyridineHCID 14479914—
ReactantHCID 178515047HCID 178515047—
Product2-[(4-Methoxy-5-methylpyridin-2-yl)methylthio]-3-phenyl4(3H)-quinazolinoneHCID 1457516422.5%

Reaction Steps

The title compound was prepared in a yield of 22.5%, using 2-mercapto-3-phenyl-4(3H)-quinazolinone in place of 2- mercapto-6-methyl-3-phenyl-4(3H)-quinazolinone and 2-chloromethyl-4-methoxy-5-methylpyridine in place of 2-chloromethylpyridine hydrochloride.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS05008266
Source datasetuspto-grants-1991_04
ORD IDord-5617cf84ff3d4c418ca2feda863d20a8
Source noteuspto-grants-1991_04